The link between Clomid and birth defects wasn’t established until recently, but several studies published since 2010 have clearly demonstrated the inherent dangers in this drug. This medication is used to increase the chances of pregnancy by altering biochemistry in the brain, particularly the hypothalamus and pituitary gland. The drug makes the body more hospitable to reproduction, but extreme caution must be taken when receiving this medication. The Food and Drug Administration (FDA) has placed this drug in Pregnancy Category X, which means it can do major damage to a developing embryo or fetus. Because it may take several days for a woman to realize she is pregnant, the medication may do damage before the patient has time to respond.
This medication inhibits estrogen receptors in the brain, mostly in the hypothalamus. This prevents excess estrogen from preventing gonadotropin release. Gonadotropins are a collection of hormones that produce several effects on the body, including making the body more amenable to reproduction. In fact, a lack of gonadotropins in the body can cause infertility. For this reason, increasing the level of gonadotropins is a common method of improving fertility. However, some medications that produce this effect can interact poorly with an already developing embryo.
A few noteworthy studies have conclusively shown the link between Clomid and birth defects. In 2010, the National Birth Defects Prevention Study, or NBDPS, reviewed the patient histories of 5,000 pregnant women. These histories were produced between 1997 and 2005 and represent a population-based, case-control study, so the methodology is sound. Of the 5,000 women, 94 used the medication while pregnant. What they found was an increased risk of several complications, many of them fatal. These findings were supported and published by the Centers for Disease Control (CDC).
Clomid Autism Lawsuit
A Harvard study of the medication’s use in pregnant women also showed a number of complications arising from usage of the drug. Harvard researchers found an incidence rate of autism spectrum disorders that was two times higher than children not exposed to the drug.
Major complications associated with the medication’s use includes anencephaly (missing part of the brain or skull), coarctation of the aorta (may result in poor blood flow to lower extremities), esophageal atresia (esophagus does not connect to stomach), omphalocele (organs normally found in the abdominal cavity are instead found outside the body), craniosynostosis (abnormal development of the skull) and septal heart complications (abnormal cellular structure inside the heart). All of these adverse effects are severe and permanent without intensive medical intervention. Without treatment, many children born with these problems will not be able to survive.
With the link between Clomid and birth defects firmly established, many parents have filed a lawsuit against the drug’s manufacturer to help pay for the expensive medical treatments needed to help their children. Many lawsuits have already been filed, and there will likely be many more in the future. Any woman who has taken this medication and had a child with severe health complications should consider speaking to an experienced drug injury attorney. Through product liability laws, a family may be able to attain justice for their child and ensure a better life for them.