Why Is Taking Proton Pump Inhibitors Leading To Law Suits?

by Terry Bryant

Though they are among the most frequently prescribed drugs in the world, patients taking proton pump inhibitors (PPIs) are filing law suits at increasing rates. PPIs are highly effective at treating gastric acid disorders. In fact, there is no other class of medications that even compares, as PPIs are 99% more effective than antagonist medications. Their effects are usually long-term, and often permanent as well, which means that they only have to be used briefly. This is important, as there is little research into long-term use of PPIs, and emerging research suggests that there are significant health complications associated with long-term PPI use.

Since 2012, several research groups have published troubling safety findings regarding proton pump inhibitors leading to law suits. In 2016, the Journal of the American Society of Nephrology found that patients that used PPIs were 95% more likely to develop serious kidney problems, including Chronic Kidney Disease or End Stage Renal Disease, both of which are extremely expensive and difficult to treat.

Also in 2016, the Pharmaceutical Journal published research that showed that patients using PPIs were 44% more likely to develop dementia, an emotionally and mentally devastating condition. Heart attacks and bone fractures have also been linked to PPI usage.

AstraZeneca is the pharmaceutical manufacturer most often linked to serious health problems, as Prilosec and Nexium are the two most popular PPIs on the market. Many claims assert that AstraZeneca was aware of these problems before research was made available, and the company has been involved in serious legal issues before.